Gene Synthesis Services

Gene Synthesis

Synbio Technologies is one of the leading companies in synthetic biology industry, especially with respect to gene synthesis. We have developed the only complete platform in the world with the Syno®1.0, 2.0, and 3.0 technologies to meet our customer’s needs in flux, delivery cycle, pricing, synthesis difficulty and other various dimensions. We are proud of being the only company within this industry to develop such a platform, and have the upmost reliability in this technology. This reliability and efficiency is seen in our production each month, resulting in the synthesis of over 2 million base pairs of DNA sequences including genes, genomes, and other various biological pathways. The resulting products are then delivered globally to our customers within an efficient timeframe.

By using molecular cloning technology, our Syno®2.0 gene synthesis platform is able to effectively complete enzymatic assembly on the basis of short DNA fragments. This in turn allows us to generate a requested genetic sequence up to and including 200kb in length. With our Syno®3.0 next generation gene synthesis platform, the cost of synthetic genes could be reduced by over 30%. Moreover, the proprietary NG®Codon software can significantly optimize the original sequences from customers. Through use of this technology, we can provide synthesized genes with 100% accuracy through our proprietary Syno®DNA synthesis and assembly technologies. Relying on the verification with Sanger sequencing, Synbio Technologies is capable of generating the highest quality output for our customers. In addition, our scientific team is experienced in dealing with the majority problems of gene synthesis. With this combination, Synbio Technologies is ready to provide our customers with a one stop location for high quality output designed to fit all of their gene synthesis needs.

According to the DNA or amino acid sequences you provided, we will de novo synthesize the error-free DNA sequences and clone them into any vector as requested. In order to provide our customers with the highest quality output, Sanger sequencing will be conducted before each of these steps in order to verify the sequence accuracy. With our professional research team and effective systems in place, we promise you a one-stop location that will satisfy all of your gene synthesis needs.

Gene Synthesis Advantages

  • Patented NG®Codon optimization software that provides free codon optimization services, enabling a significant increase in protein expression.
  • The only complete platform in the world with the entire Syno®1.0-3.0 technologies to meet the customer needs in flux, delivery cycle, pricing, synthesis difficulty and other different dimensions.
  • Syno®Assembly technology ensures reliable assembly of long DNA fragments, single gene sequence up to 200Kb.
  • Guarantee 100% sequence accuracy for all genes delivered by Synbio Technologies.
  • All intellectual property (IP) information including: DNA sequence and its related information are kept strictly confidential in the entire process by Synbio Technologies.
Syno® 2.0 Gene Synthesis
100% sequence accuracy, effectively deliver complex sequences including repetitive, strong hairpin, high GC content sequences
Syno® 3.0 Gene Synthesis
Next generation DNA synthesis platform, high throughput and cost effective, gene synthesis starts at $0.09/bp, 100% sequence accuracy
NG® Codon Optimization
Patented codon optimization technology, increase of protein expression level in most host cells
Vector Construction
shRNA, TALEN, CRISPR-Cas9 construction and validation
Small Genome Synthesis & Assembly
Synthesis and Assembly Services on Gene Cluster and Small Genome, guarantee 100% accuracy on all of your delivered DNA orders
Pathway Synthesis & Assembly
Proprietary metabolic pathway design platform, Syno® Assembly technology ensures long gene synthesis up to 200 kbp

Gene Synthesis Service Specifications:

Gene Length Order Size Codon Optimization Price Turnaround Time
(business days)
< 1.5 kb <100 kbp Free (optional) Starts at $0.19/bp
Quote
7-10
100-200 kbp Free (optional) Starts at $0.12/bp
Quote
20-35
200-500 kbp Free (optional) Starts at $0.10/bp
Quote
Quote
>500 kbp Free (optional) Starts at $0.09/bp
Quote
Quote
1.5-4 kb <100 kbp Free (optional) Quote 10-15
≥ 100 kbp Free (optional) Quote Quote
4-6 kb <100 kbp Free (optional) Quote 20-25
≥ 100 kbp Free (optional) Quote Quote
6-9 kb <100 kbp Free (optional) Quote 25-30
≥ 100 kbp Free (optional) Quote Quote
> 9 kb <100 kbp Free (optional) Quote Quote
≥ 100 kbp Free (optional) Quote Quote

Note: The turnaround time and price apply to the non-complex sequences. Please contact service@synbio-tech.com to quote for the complex sequences.

Vector Information:

Vector type Antibiotic resistance Multiple clone sites
Puc57-Amp Ampr Yes
Puc57-Kan Kanr Yes

Delivery form:
Synbio Technologies’ standard package including:

  • 4 µg of lyophilized plasmid DNA
  • Sequencing chromatogram
  • Certificate of analysis (COA)

Gene Synthesis Wiki

Related Services:

How to order gene synthesis services

online-quotation
Online Inquiry
email
service@synbio-tech.com
call
+1 732-230-3003
fax
+1 609 228 5911

Submit gene/protein sequence: Gene synthesis online inquiry.