Oligo Modification & Labeling



Synbio Technologies provides comprehensive modifications and labeling services to meet our customer’s specified research requirements. Our industry leading professional team utilizes state-of-the-art synthesizers to achieve both oligo synthesis and modifications. Our stringent quality control guidelines ensure the synthesis of high-quality modified oligos and subsequently delivered in a timely manner. In doing so, we will assist you with various research needs in biology, diagnostics, personal medicine, drug discovery, etc.

Synbio Technologies’ custom DNA oligos are designed and synthesized with rigorous quality control to ensure that overall quality while meeting our customers’ every request. Our specialized services include oligonucleotides modified with special bases, dU/dI, phosphorothioates, phosphorylation, spacers, amino linkers, disulfide linkers, biotin, digoxin, etc. Synbio Technologies also provides multiple fluorescent groups and quenchers at 3’, 5’ or designated sites specified by the customer. This includes FAM, HEX, ROX, BHQ and Texas Red, etc. The resulting oligos can be used in a variety of applications, including PCR, cloning, sequence verification, and gene detection.

Competitive Advantages

  • Comprehensive Modifications and Labeling:

  • Large-scale sequencing verifying the average mutation rate to be lower than 1/1000

  • Stringent ISO9001:

  • 2015 Certified Processing for oligo synthesis, meticulously monitored and advanced traceability

  • Multiple Purification Options:

  • Include desalt, PAGEE Plus, PAGEE, RP-HPLC, IE-HPLC and Dual HPLC

  • Technical Support:

  • Professional teams experienced in oligo synthesis and various modifications offer support throughout the production progress

Service Specifications

Synbio Technologies provides a series of general modifications with the high purity and competitive prices. We accomplish this by focusing on the requests of modification with special chemical classifications. Browse general modifications listed below:

Classifications Modifications Purification
(10-45bp) (46-80bp)
Modified Bases dU RP-HPLC PAGE&RP-HPLC
dI
5-Methyl dC
DBCO 5’ DBCO RP-HPLC RP-HPLC
3’ DBCO PAGE&RP-HPLC
dT-DBCO
AMCA 5’ AMCA RP-HPLC RP-HPLC
3’ AMCA PAGE&RP-HPLC
dT-AMCA
Phosphorothioates SPO3 RP-HPLC PAGE&RP-HPLC
Amino Linkers 5’Amino C6 RP-HPLC PAGE&RP-HPLC
dT-Amino C6
3’Amino C7
5’Amino C12 RP-HPLC
Biotin 5’Biotin RP-HPLC RP-HPLC
3’Biotin PAGE&RP-HPLC
dT-Biotin
Digoxigenin 5’Digoxigenin RP-HPLC RP-HPLC
3’Digoxigenin PAGE&RP-HPLC
dT-Digoxigenin
Phosphorylation 5’ PO4 RP-HPLC PAGE&RP-HPLC
3’ PO4
Hydrosulphonyl 5’ HS-C6 RP-HPLC RP-HPLC
3’ HS-C3 PAGE&RP-HPLC
Locked Nuleic Acid LNA (A/G/C/U) RP-HPLC PAGE&RP-HPLC
Fluoro Bases 2’-F-2’-dA
2’-F-2’-dC
2’-F-2’-dG
2’-F-2’-dU
RP-HPLC PAGE&RP-HPLC
Spacer dSpacer RP-HPLC PAGE&RP-HPLC
Spacer C3
Spacer C9
Spacer C18

Standard Deliverables

  1. Lyophilized dry DNA oligo powder
  2. 1 tube (Transparent or dark) or 96-well and 384-well plate
  3. Certificate of Analysis (COA) including sequencing information, OD, Tm, etc.

How to Order Oligo Modification & Labeling

If you have any questions, please feel free to contact us anytime for assistance during business hours. Our experienced project managers will provide you with professional support to ensure the success of your project.

online-quotation
Online Inquiry
email
service@synbio-tech.com
call
+1 732-230-3003
fax
+1 609 228 5911