Customer Academic Publications-Gene Synthesis

Junmei H, Gudong L, Chaoqun L,et al. Stereoselective synthesis of the key intermediate of ticagrelor and its diverse analogs using a new alcohol dehydrogenase from Rhodococcus kyotonensis.Process Biochemistry,Volume 92, May 2020, Pages 232-243. doi:10.1016/j.procbio.2020.01.015

Caixia C, HongMing L, jing L,et al. Fabrication of an in-situ co-immobilized enzyme in mesoporous silica for synthesizing GSH with ATP regeneration.Molecular Catalysis, Volume 486, May 2020, 110870. doi:10.1016/j.mcat.2020.110870

Shu C, Qian W, Bing H,et al. Effects of leptin-modified human placenta-derived mesenchymal stem cells on angiogenic potential and peripheral inflammation of human umbilical vein endothelial cells (HUVECs) after X-ray radiation.J Zhejiang Univ Sci B. 2020. doi: 10.1631/jzus.B1900598

Christian Müller, Phil Lukas, Dana Sponholz,et al. The hirudin-like factors HLF3 and HLF4—hidden hirudins of European medicinal leeches.Parasitology Research volume 119, 1767-1775(2020). doi:10.1007/s00436-020-06697-1

Yajie G, Yafang W, Anthony J,et al. Engineering of multiple trypsin/chymotrypsin sites in Cry3A to enhance its activity against Monochamus alternatus Hope larvae.Pest Management Science. doi:10.1002/ps.5866

Huang, J., Zha, W., An, T. et al. Appl Microbiol Biotechnol (2019) 103: 7029. Identification of RoCYP01 (CYP716A155) enables construction of engineered yeast for high-yield production of betulinic acid doi:10.1007/s00253-019-10004-z

Wang, Z.-P.; Zhang, L.-L.; Liu, S.; Liu, X.-Y.; Yu, X.-J. Whole Conversion of Soybean Molasses into Isomaltulose and Ethanol by Combining Enzymatic Hydrolysis and Successive Selective Fermentations. Biomolecules 2019, 9, 353. doi: 10.3390/biom9080353

Moog, D., Schmitt, J., Senger, J. et al. Using a marine microalga as a chassis for polyethylene terephthalate (PET) degradation Microb Cell Fact (2019) 18: 171.doi:10.1186/s12934-019-1220-z

Proietti, S.; Falconieri, G.S.; Bertini, L.; Baccelli, I.; Paccosi, E.; Belardo, A.; Timperio, A.M.; Caruso, C. GLYI4 Plays A Role in Methylglyoxal Detoxification and Jasmonate-Mediated Stress Responses in Arabidopsis thaliana. Biomolecules 2019, 9, 635 doi:10.3390/biom9100635

Xu Y , Li Y , Zhang L , et al. Unraveling the specific regulation of the shikimate pathway for tyrosine accumulation in Bacillus licheniformis[J]. Journal of Industrial Microbiology and Biotechnology, 2019, 46(8). doi:10.1007/s10295-019-02213-2

Chen Y J, Zhang J, Zhu P P, et al. Stereoselective Oxidation Kinetics of Deoxycholate in Recombinant and Microsomal CYP3A Enzymes: Deoxycholate 19-hydroxylation is an In Vitro Marker of CYP3A7 Activity[J]. Drug Metabolism and Disposition, 2019: dmd. 119.086637. doi:10.1124/dmd.119.086637

Jiang S, Jiang H, Zhou Y, et al. High-level expression of β-N-Acetylglucosaminidase BsNagZ in Pichia pastoris to obtain GlcNAc[J]. Bioprocess and biosystems engineering, 2019, 42(4): 611-619. doi:10.1007/s00449-018-02067-5

Li S Y, Wang Z P, Wang L N, et al. Combined enzymatic hydrolysis and selective fermentation for green production of alginate oligosaccharides from Laminaria japonica[J]. Bioresource technology, 2019, 281: 84-89. doi:10.1016/j.biortech.2019.02.056

Zhang F, Wang W, Bah F B M, et al. Heterologous Expression of a Thermostable α-Glucosidase from Geobacillus sp. Strain HTA-462 by Escherichia coli and Its Potential Application for Isomaltose–Oligosaccharide Synthesis[J]. Molecules, 2019, 24(7): 1413. doi:10.3390/molecules24071413

Orlomoski R, Bogle A, Loss J, et al. Rapid and efficient purification of Drosophila homeodomain transcription factors for biophysical characterization[J]. Protein expression and purification, 2019, 158: 9-14. doi:10.1016/j.pep.2019.02.001

Su Y, Han M, Meng X, et al. Discovery and characterization of a novel C-terminal peptide carboxyl methyltransferase in a lassomycin-like lasso peptide biosynthetic pathway[J]. Applied microbiology and biotechnology, 2019: 1-16. doi:10.1007/s00253-019-09645-x

Zhou L, Sheng D, Wang D, et al. Identification of cancer-type specific expression patterns for active aldehyde dehydrogenase (ALDH) isoforms in ALDEFLUOR assay[J]. Cell biology and toxicology, 2019, 35(2): 161-177. doi:10.1007/s10565-018-9444-y

Wanitchang A, Saenboonrueng J, Kaewborisuth C, et al. A Single V672F Substitution in the Spike Protein of Field-Isolated PEDV Promotes Cell–Cell Fusion and Replication in VeroE6 Cells[J]. Viruses, 2019, 11(3): 282. doi:10.3390/v11030282

Zhang P, Wang Z P, Liu S, et al. Overexpression of secreted sucrose isomerase in Yarrowia lipolytica and its application in isomaltulose production after immobilization[J]. International journal of biological macromolecules, 2019, 121: 97-103. doi:10.1016/j.ijbiomac.2018.10.010

Liu H, Chen D, Bi J, et al. Circular RNA circUBXN7 represses cell growth and invasion by sponging miR-1247-3p to enhance B4GALT3 expression in bladder cancer[J]. Aging (Albany NY), 2018, 10(10): 2606. doi:10.18632/aging.101573

Yao Y, Li S, Cao J, et al. A novel signal transduction system for development of uric acid biosensors[J]. Applied microbiology and biotechnology, 2018, 102(17): 7489-7497. doi:10.1007/s00253-018-9056-8

Wanitchang A, Saenboonrueng J, Srisutthisamphan K, et al. Characterization of influenza A virus pseudotyped with the spike protein of porcine epidemic diarrhea virus[J]. Archives of virology, 2018, 163(12): 3255-3264. doi:10.1007/s00705-018-4001-9

Wu Y, Jiang Y, Zheng X, et al. Facile fabrication of microfluidic surface-enhanced Raman scattering devices via lift-up lithography[J]. Royal Society open science, 2018, 5(4): 172034. doi:10.1098/rsos.172034

Gong, S., & Wu, C. (2019, February 1). Generation of Fabs-in-tandem immunoglobulin molecules for dual-specific targeting. Methods,154, 87-92. doi:10.1016/j.ymeth.2018.07.014

Eastwood M P, Deprest J, Russo F M, et al. MicroRNA 200b is upregulated in the lungs of fetal rabbits with surgically induced diaphragmatic hernia[J]. Prenatal diagnosis, 2018, 38(9): 645-653. doi:10.1002/pd.5318

Johnston C D, Cotton S L, Rittling S R, et al. SyngenicDNA: stealth-based evasion of restriction-modification barriers during bacterial genetic engineering[J]. bioRxiv, 2018: 387985. doi:10.1101/387985

Lu H, Bai Y, Fan T, et al. Identification of a L-Lactate dehydrogenase with 3, 4-dihydroxyphenylpyruvic reduction activity for L-Danshensu production[J]. Process Biochemistry, 2018, 72: 119-123. doi:10.1016/j.procbio.2018.06.011

Chu J, Li Y, Fan X, et al. MiR-4319 suppress the malignancy of triple-negative breast cancer by regulating self-renewal and tumorigenesis of stem cells[J]. Cellular Physiology and Biochemistry, 2018, 48(2): 593-604. doi:10.1159/000491888

Peng C, Liu Y, Guo X, et al. Selective carboxylation of substituted phenols with engineered Escherichia coli whole-cells[J]. Tetrahedron letters, 2018, 59(42): 3810-3815. doi:10.1016/j.tetlet.2018.09.019

Hu X X, Xu X N, He B S, et al. microRNA-485-5p functions as a tumor suppressor in colorectal cancer cells by targeting CD147[J]. Journal of Cancer, 2018, 9(15): 2603. doi:10.7150/jca.24918

Chang, Z., Meng, F., Zhang, Z., Mao, G., Huang, Z., Liao, W., & He, A. (2018). MicroRNA-193b-3p regulates matrix metalloproteinase 19 expression in interleukin-1β-induced human chondrocytes. Journal of Cellular Biochemistry,119(6), 4775-4782. doi:10.1002/jcb.26669

Cheng, Y., Chen, G., Wang, L., Kong, J., Pan, J., Xi, Y., . . . Huang, Z. (2018). Triptolide-induced mitochondrial damage dysregulates fatty acid metabolism in mouse sertoli cells. Toxicology Letters,292, 136-150. doi:10.1016/j.toxlet.2018.04.035

Hu, X., Xu, X., He, B., Sun, H., Xu, T., Liu, X., . . . Pan, Y. (2018). MicroRNA-485-5p Functions as a Tumor Suppressor in Colorectal Cancer Cells by Targeting CD147. Journal of Cancer,9(15), 2603-2611. doi:10.7150/jca.24918

Jin, W., Li, S., Chen, J., Liu, B., Li, J., Li, X., . . . Zhong, W. (2018). Increased soluble heterologous expression of a rat brain 3- O -sulfotransferase 1 – A key enzyme for heparin biosynthesis. Protein Expression and Purification,151, 23-29. doi:10.1016/j.pep.2018.06.007

Li, J., Zhang, Y., Zhang, Y., Lü, S., Miao, Y., Yang, J., . . . Feng, J. (2018). GSNOR modulates hyperhomocysteinemia-induced T cell activation and atherosclerosis by switching Akt S-nitrosylation to phosphorylation. Redox Biology,17, 386-399. doi:10.1016/j.redox.2018.04.021

Pan, Y., Sun, H., Hu, X., He, B., Liu, X., Xu, T., . . . Wang, S. (2018). The inhibitory role of miR‑485‑5p in colorectal cancer proliferation and invasion via targeting of CD147. Oncology Reports. doi:10.3892/or.2018.6309

Peng, C., Liu, Y., Guo, X., Liu, W., Li, Q., & Zhao, Z. K. (2018, October 17). Selective carboxylation of substituted phenols with engineered Escherichia coli whole-cells. Tetrahedron Letters,59(42), 3810-3815. doi:10.1016/j.tetlet.2018.09.019

Shi, J., Wang, X., Zhu, H., Jiang, H., Wang, D., Nesvizhskii, A., & Zhu, H. (2018, August 24). Determining Allele-Specific Protein Expression (ASPE) Using a Novel Quantitative Concatamer Based Proteomics Method. Journal of Proteome Research,17(10), 3606-3612. doi:10.1021/acs.jproteome.8b00620

Shi, J., Wang, X., Zhu, H., Jiang, H., Wang, D., Nesvizhskii, A., & Zhu, H. (2018). Determining Allele-Specific Protein Expression (ASPE) Using a QconCAT-Based Proteomics Method: A Novel Approach to Identify Cis-acting Genetic Variants. doi:10.1101/264614

Lu, H., Bai, Y., Fan, T., Zhao, Y., Zheng, X., & Cai, Y. (2018). Identification of a l -Lactate dehydrogenase with 3,4-dihydroxyphenylpyruvic reduction activity for l -Danshensu production. Process Biochemistry,72, 119-123. doi:10.1016/j.procbio.2018.06.011

Yang, X., Sun, W., Shen, H., Zhang, S., Jiao, X., & Zhao, Z. K. (2018). Expression of phosphotransacetylase in Rhodosporidium toruloides leading to improved cell growth and lipid production. RSC Advances,8(43), 24673-24678. doi:10.1039/c8ra03028f

Zhang, W., He, Z., Yi, L., Mao, S., Li, H., & Lin, J. (2018). A dual-functional microfluidic chip for on-line detection of interleukin-8 based on rolling circle amplification. Biosensors and Bioelectronics,102, 652-660. doi:10.1016/j.bios.2017.12.017

Wang, J., Chen, S., Xiao, W., Li, W., Wang, L., Yang, S., . . . Zhou, P. (2018, January 10). CAR-T cells targeting CLL-1 as an approach to treat acute myeloid leukemia. Journal of Hematology & Oncology,11(1). doi:10.1186/s13045-017-0553-5

Zhao, Z., Xue, J., Song, Y., Liu, T., & Piao, D. (2017). Downregulated long non‑coding RNA TCONS_00068220 upregulates apoptosis in gastric cancer cells. Oncology Letters. doi:10.3892/ol.2017.6977

Wang, L., Liang, C., Wu, J., Liu, L., & Tyo, K. E. (2017). Increased Processivity, Misincorporation, and Nucleotide Incorporation Efficiency in Sulfolobus solfataricus Dpo4 Thumb Domain Mutants. Applied and Environmental Microbiology,83(18). doi:10.1128/aem.01013-17

Wang, X., Zhou, Y. J., Wang, L., Liu, W., Liu, Y., Peng, C., & Zhao, Z. K. (2017). Engineering Escherichia coli Nicotinic Acid Mononucleotide Adenylyltransferase for Fully Active Amidated NAD Biosynthesis. Applied and Environmental Microbiology,83(13). doi:10.1128/aem.00692-17

Wang, X., Wang, L., Lin, X., Yang, X., Liu, W., & Zhao, Z. K. (2017). Visualizing Soluble Protein Mutants by Using Monomeric Red Fluorescent Protein as a Reporter for Directed Evolution. Applied Biochemistry and Biotechnology,185(1), 81-90. doi:10.1007/s12010-017-2640-z

Xie, Z., Liu, D., Li, B., Zhao, M., Zeng, B., Wu, Y., . . . Yuan, Y. (2017). Design and chemical synthesis of eukaryotic chromosomes. Chemical Society Reviews,46(23), 7191-7207. doi:10.1039/c7cs00208d

Liu, J., Chen, W., Zhang, H., Liu, T., & Zhao, L. (2017). MiR‑214 targets the PTEN‑mediated PI3K/Akt signaling pathway and regulates cell proliferation and apoptosis in ovarian cancer. Oncology Letters. doi:10.3892/ol.2017.6953

Dai, S., Zhang, J., Huang, S., Lou, B., Fang, B., Ye, T., . . . Zhou, M. (2017). HNRNPA2B1 regulates the epithelial–mesenchymal transition in pancreatic cancer cells through the ERK/snail signalling pathway. Cancer Cell International,17(1). doi:10.1186/s12935-016-0368-4

Duan, L., Ding, W., Liu, X., Cheng, X., Cai, J., Hua, E., & Jiang, H. (2017). Biosynthesis and engineering of kaempferol in Saccharomyces cerevisiae. Microbial Cell Factories,16(1). doi:10.1186/s12934-017-0774-x

He, P., Li, Y., Luo, J., Wang, H., Yan, Y., & Chen, Z. (2017). Development and Application of A Duplex Real-Time RT-PCR Assay for Simultaneous Detection of Coxsackievirus A6 and Coxsackievirus A10. Ann Clin Lab Sci,47(March), 2nd ser., 178-183. PMID: 28442520

Jin, L., Miao, J., Liu, Y., Li, X., Jie, Y., Niu, Q., & Han, X. (2017). Icaritin induces mitochondrial apoptosis by up-regulating miR-124 in human oral squamous cell carcinoma cells. Biomedicine & Pharmacotherapy,85, 287-295. doi:10.1016/j.biopha.2016.11.023

Su, J., Gao, J., Si, Y., Cui, L., Song, C., Wang, Y., . . . Zhou, Y. (2017, March). Galectin-10: A new structural type of prototype galectin dimer and effects on saccharide ligand binding. Glycobiology,28(3), 159-168. doi:10.1093/glycob/cwx107

Li, N., Yi, L., He, Z., Zhang, W., Li, H., & Lin, J. (2017). A DNA-directed covalent conjugation fluorescence probe for in vitro detection of functional matrix metalloproteinases. The Analyst,142(4), 634-640. doi:10.1039/c6an02339h

Si Y, Wang Y, Gao J, et al. Crystallization of galectin-8 linker reveals intricate relationship between the N-terminal tail and the linker[J]. International journal of molecular sciences, 2016, 17(12): 2088. doi:10.3390/ijms17122088

Li, Z., Feng, S., Zhou, L., Liu, S., & Cheng, J. (2016). NS5ATP6 modulates intracellular triglyceride content through FGF21 and independently of SIRT1 and SREBP1. Biochemical and Biophysical Research Communications,475(1), 133-139. doi:10.1016/j.bbrc.2016.05.056

Na, R., Jiajia, L., Dongliang, Y., Yingzi, P., Juan, H., Xiong, L., . . . Yitian, L. (2016). Indentification of vincamine indole alkaloids producing endophytic fungi isolated from Nerium indicum , Apocynaceae. Microbiological Research,192, 114-121. doi:10.1016/j.micres.2016.06.008

Pan, X., Wang, H., Tong, D., Wang, C., Sun, L., Zhao, C., . . . Wu, D. (2016). Physcion induces apoptosis in hepatocellular carcinoma by modulating miR-370. Am J Cancer Res,6(Dec), 12th ser., 2919-2931. PMID: 28042511

Si, X., Zhang, X., Hao, X., Li, Y., Chen, Z., Ding, Y., . . . Zhou, Y. (2016). Upregulation of miR-99a is associated with poor prognosis of acute myeloid leukemia and promotes myeloid leukemia cell expansion. Oncotarget,7(47). doi:10.18632/oncotarget.12947

Tang, Y., Cui, Y., Li, Z., Jiao, Z., Zhang, Y., He, Y., . . . Zhang, S. (2016). Radiation-induced miR-208a increases the proliferation and radioresistance by targeting p21 in human lung cancer cells. Journal of Experimental & Clinical Cancer Research,35(1). doi:10.1186/s13046-016-0285-3

Yang, H., Zhu, Q., Zhou, N., & Tian, Y. (2016). Optimized expression of prolyl aminopeptidase in Pichia pastoris and its characteristics after glycosylation. World Journal of Microbiology and Biotechnology,32(11). doi:10.1007/s11274-016-2135-z