Gene Synthesis
Chen Y J, Zhang J, Zhu P P, et al. Stereoselective Oxidation Kinetics of Deoxycholate in Recombinant and Microsomal CYP3A Enzymes: Deoxycholate 19-hydroxylation is an In Vitro Marker of CYP3A7 Activity[J]. Drug Metabolism and Disposition, 2019: dmd. 119.086637. doi:10.1124/dmd.119.086637
Jiang S, Jiang H, Zhou Y, et al. High-level expression of β-N-Acetylglucosaminidase BsNagZ in Pichia pastoris to obtain GlcNAc[J]. Bioprocess and biosystems engineering, 2019, 42(4): 611-619. doi:10.1007/s00449-018-02067-5
Li S Y, Wang Z P, Wang L N, et al. Combined enzymatic hydrolysis and selective fermentation for green production of alginate oligosaccharides from Laminaria japonica[J]. Bioresource technology, 2019, 281: 84-89. doi:10.1016/j.biortech.2019.02.056
Zhang F, Wang W, Bah F B M, et al. Heterologous Expression of a Thermostable α-Glucosidase from Geobacillus sp. Strain HTA-462 by Escherichia coli and Its Potential Application for Isomaltose–Oligosaccharide Synthesis[J]. Molecules, 2019, 24(7): 1413. doi:10.3390/molecules24071413
Orlomoski R, Bogle A, Loss J, et al. Rapid and efficient purification of Drosophila homeodomain transcription factors for biophysical characterization[J]. Protein expression and purification, 2019, 158: 9-14. doi:10.1016/j.pep.2019.02.001
Su Y, Han M, Meng X, et al. Discovery and characterization of a novel C-terminal peptide carboxyl methyltransferase in a lassomycin-like lasso peptide biosynthetic pathway[J]. Applied microbiology and biotechnology, 2019: 1-16. doi:10.1007/s00253-019-09645-x
Zhou L, Sheng D, Wang D, et al. Identification of cancer-type specific expression patterns for active aldehyde dehydrogenase (ALDH) isoforms in ALDEFLUOR assay[J]. Cell biology and toxicology, 2019, 35(2): 161-177. doi:10.1007/s10565-018-9444-y
Wanitchang A, Saenboonrueng J, Kaewborisuth C, et al. A Single V672F Substitution in the Spike Protein of Field-Isolated PEDV Promotes Cell–Cell Fusion and Replication in VeroE6 Cells[J]. Viruses, 2019, 11(3): 282. doi:10.3390/v11030282
Zhang P, Wang Z P, Liu S, et al. Overexpression of secreted sucrose isomerase in Yarrowia lipolytica and its application in isomaltulose production after immobilization[J]. International journal of biological macromolecules, 2019, 121: 97-103. doi:10.1016/j.ijbiomac.2018.10.010
Liu H, Chen D, Bi J, et al. Circular RNA circUBXN7 represses cell growth and invasion by sponging miR-1247-3p to enhance B4GALT3 expression in bladder cancer[J]. Aging (Albany NY), 2018, 10(10): 2606. doi:10.18632/aging.101573
Yao Y, Li S, Cao J, et al. A novel signal transduction system for development of uric acid biosensors[J]. Applied microbiology and biotechnology, 2018, 102(17): 7489-7497. doi:10.1007/s00253-018-9056-8
Wanitchang A, Saenboonrueng J, Srisutthisamphan K, et al. Characterization of influenza A virus pseudotyped with the spike protein of porcine epidemic diarrhea virus[J]. Archives of virology, 2018, 163(12): 3255-3264. doi:10.1007/s00705-018-4001-9
Wu Y, Jiang Y, Zheng X, et al. Facile fabrication of microfluidic surface-enhanced Raman scattering devices via lift-up lithography[J]. Royal Society open science, 2018, 5(4): 172034. doi:10.1098/rsos.172034
Gong, S., & Wu, C. (2019, February 1). Generation of Fabs-in-tandem immunoglobulin molecules for dual-specific targeting. Methods,154, 87-92. doi:10.1016/j.ymeth.2018.07.014
Eastwood M P, Deprest J, Russo F M, et al. MicroRNA 200b is upregulated in the lungs of fetal rabbits with surgically induced diaphragmatic hernia[J]. Prenatal diagnosis, 2018, 38(9): 645-653. doi:10.1002/pd.5318
Johnston C D, Cotton S L, Rittling S R, et al. SyngenicDNA: stealth-based evasion of restriction-modification barriers during bacterial genetic engineering[J]. bioRxiv, 2018: 387985. doi:10.1101/387985
Lu H, Bai Y, Fan T, et al. Identification of a L-Lactate dehydrogenase with 3, 4-dihydroxyphenylpyruvic reduction activity for L-Danshensu production[J]. Process Biochemistry, 2018, 72: 119-123. doi:10.1016/j.procbio.2018.06.011
Chu J, Li Y, Fan X, et al. MiR-4319 suppress the malignancy of triple-negative breast cancer by regulating self-renewal and tumorigenesis of stem cells[J]. Cellular Physiology and Biochemistry, 2018, 48(2): 593-604. doi:10.1159/000491888
Peng C, Liu Y, Guo X, et al. Selective carboxylation of substituted phenols with engineered Escherichia coli whole-cells[J]. Tetrahedron letters, 2018, 59(42): 3810-3815. doi:10.1016/j.tetlet.2018.09.019
Hu X X, Xu X N, He B S, et al. microRNA-485-5p functions as a tumor suppressor in colorectal cancer cells by targeting CD147[J]. Journal of Cancer, 2018, 9(15): 2603. doi:10.7150/jca.24918
Chang, Z., Meng, F., Zhang, Z., Mao, G., Huang, Z., Liao, W., & He, A. (2018). MicroRNA-193b-3p regulates matrix metalloproteinase 19 expression in interleukin-1β-induced human chondrocytes. Journal of Cellular Biochemistry,119(6), 4775-4782. doi:10.1002/jcb.26669
Cheng, Y., Chen, G., Wang, L., Kong, J., Pan, J., Xi, Y., . . . Huang, Z. (2018). Triptolide-induced mitochondrial damage dysregulates fatty acid metabolism in mouse sertoli cells. Toxicology Letters,292, 136-150. doi:10.1016/j.toxlet.2018.04.035
Hu, X., Xu, X., He, B., Sun, H., Xu, T., Liu, X., . . . Pan, Y. (2018). MicroRNA-485-5p Functions as a Tumor Suppressor in Colorectal Cancer Cells by Targeting CD147. Journal of Cancer,9(15), 2603-2611. doi:10.7150/jca.24918
Jin, W., Li, S., Chen, J., Liu, B., Li, J., Li, X., . . . Zhong, W. (2018). Increased soluble heterologous expression of a rat brain 3- O -sulfotransferase 1 – A key enzyme for heparin biosynthesis. Protein Expression and Purification,151, 23-29. doi:10.1016/j.pep.2018.06.007
Li, J., Zhang, Y., Zhang, Y., Lü, S., Miao, Y., Yang, J., . . . Feng, J. (2018). GSNOR modulates hyperhomocysteinemia-induced T cell activation and atherosclerosis by switching Akt S-nitrosylation to phosphorylation. Redox Biology,17, 386-399. doi:10.1016/j.redox.2018.04.021
Pan, Y., Sun, H., Hu, X., He, B., Liu, X., Xu, T., . . . Wang, S. (2018). The inhibitory role of miR‑485‑5p in colorectal cancer proliferation and invasion via targeting of CD147. Oncology Reports. doi:10.3892/or.2018.6309
Peng, C., Liu, Y., Guo, X., Liu, W., Li, Q., & Zhao, Z. K. (2018, October 17). Selective carboxylation of substituted phenols with engineered Escherichia coli whole-cells. Tetrahedron Letters,59(42), 3810-3815. doi:10.1016/j.tetlet.2018.09.019
Shi, J., Wang, X., Zhu, H., Jiang, H., Wang, D., Nesvizhskii, A., & Zhu, H. (2018, August 24). Determining Allele-Specific Protein Expression (ASPE) Using a Novel Quantitative Concatamer Based Proteomics Method. Journal of Proteome Research,17(10), 3606-3612. doi:10.1021/acs.jproteome.8b00620
Shi, J., Wang, X., Zhu, H., Jiang, H., Wang, D., Nesvizhskii, A., & Zhu, H. (2018). Determining Allele-Specific Protein Expression (ASPE) Using a QconCAT-Based Proteomics Method: A Novel Approach to Identify Cis-acting Genetic Variants. doi:10.1101/264614
Lu, H., Bai, Y., Fan, T., Zhao, Y., Zheng, X., & Cai, Y. (2018). Identification of a l -Lactate dehydrogenase with 3,4-dihydroxyphenylpyruvic reduction activity for l -Danshensu production. Process Biochemistry,72, 119-123. doi:10.1016/j.procbio.2018.06.011
Yang, X., Sun, W., Shen, H., Zhang, S., Jiao, X., & Zhao, Z. K. (2018). Expression of phosphotransacetylase in Rhodosporidium toruloides leading to improved cell growth and lipid production. RSC Advances,8(43), 24673-24678. doi:10.1039/c8ra03028f
Zhang, W., He, Z., Yi, L., Mao, S., Li, H., & Lin, J. (2018). A dual-functional microfluidic chip for on-line detection of interleukin-8 based on rolling circle amplification. Biosensors and Bioelectronics,102, 652-660. doi:10.1016/j.bios.2017.12.017
Wang, J., Chen, S., Xiao, W., Li, W., Wang, L., Yang, S., . . . Zhou, P. (2018, January 10). CAR-T cells targeting CLL-1 as an approach to treat acute myeloid leukemia. Journal of Hematology & Oncology,11(1). doi:10.1186/s13045-017-0553-5
Zhao, Z., Xue, J., Song, Y., Liu, T., & Piao, D. (2017). Downregulated long non‑coding RNA TCONS_00068220 upregulates apoptosis in gastric cancer cells. Oncology Letters. doi:10.3892/ol.2017.6977
Wang, L., Liang, C., Wu, J., Liu, L., & Tyo, K. E. (2017). Increased Processivity, Misincorporation, and Nucleotide Incorporation Efficiency in Sulfolobus solfataricus Dpo4 Thumb Domain Mutants. Applied and Environmental Microbiology,83(18). doi:10.1128/aem.01013-17
Wang, X., Zhou, Y. J., Wang, L., Liu, W., Liu, Y., Peng, C., & Zhao, Z. K. (2017). Engineering Escherichia coli Nicotinic Acid Mononucleotide Adenylyltransferase for Fully Active Amidated NAD Biosynthesis. Applied and Environmental Microbiology,83(13). doi:10.1128/aem.00692-17
Wang, X., Wang, L., Lin, X., Yang, X., Liu, W., & Zhao, Z. K. (2017). Visualizing Soluble Protein Mutants by Using Monomeric Red Fluorescent Protein as a Reporter for Directed Evolution. Applied Biochemistry and Biotechnology,185(1), 81-90. doi:10.1007/s12010-017-2640-z
Xie, Z., Liu, D., Li, B., Zhao, M., Zeng, B., Wu, Y., . . . Yuan, Y. (2017). Design and chemical synthesis of eukaryotic chromosomes. Chemical Society Reviews,46(23), 7191-7207. doi:10.1039/c7cs00208d
Liu, J., Chen, W., Zhang, H., Liu, T., & Zhao, L. (2017). MiR‑214 targets the PTEN‑mediated PI3K/Akt signaling pathway and regulates cell proliferation and apoptosis in ovarian cancer. Oncology Letters. doi:10.3892/ol.2017.6953
Dai, S., Zhang, J., Huang, S., Lou, B., Fang, B., Ye, T., . . . Zhou, M. (2017). HNRNPA2B1 regulates the epithelial–mesenchymal transition in pancreatic cancer cells through the ERK/snail signalling pathway. Cancer Cell International,17(1). doi:10.1186/s12935-016-0368-4
Duan, L., Ding, W., Liu, X., Cheng, X., Cai, J., Hua, E., & Jiang, H. (2017). Biosynthesis and engineering of kaempferol in Saccharomyces cerevisiae. Microbial Cell Factories,16(1). doi:10.1186/s12934-017-0774-x
He, P., Li, Y., Luo, J., Wang, H., Yan, Y., & Chen, Z. (2017). Development and Application of A Duplex Real-Time RT-PCR Assay for Simultaneous Detection of Coxsackievirus A6 and Coxsackievirus A10. Ann Clin Lab Sci,47(March), 2nd ser., 178-183. PMID: 28442520
Jin, L., Miao, J., Liu, Y., Li, X., Jie, Y., Niu, Q., & Han, X. (2017). Icaritin induces mitochondrial apoptosis by up-regulating miR-124 in human oral squamous cell carcinoma cells. Biomedicine & Pharmacotherapy,85, 287-295. doi:10.1016/j.biopha.2016.11.023
Su, J., Gao, J., Si, Y., Cui, L., Song, C., Wang, Y., . . . Zhou, Y. (2017, March). Galectin-10: A new structural type of prototype galectin dimer and effects on saccharide ligand binding. Glycobiology,28(3), 159-168. doi:10.1093/glycob/cwx107
Li, N., Yi, L., He, Z., Zhang, W., Li, H., & Lin, J. (2017). A DNA-directed covalent conjugation fluorescence probe for in vitro detection of functional matrix metalloproteinases. The Analyst,142(4), 634-640. doi:10.1039/c6an02339h
Li, Z., Feng, S., Zhou, L., Liu, S., & Cheng, J. (2016). NS5ATP6 modulates intracellular triglyceride content through FGF21 and independently of SIRT1 and SREBP1. Biochemical and Biophysical Research Communications,475(1), 133-139. doi:10.1016/j.bbrc.2016.05.056
Na, R., Jiajia, L., Dongliang, Y., Yingzi, P., Juan, H., Xiong, L., . . . Yitian, L. (2016). Indentification of vincamine indole alkaloids producing endophytic fungi isolated from Nerium indicum , Apocynaceae. Microbiological Research,192, 114-121. doi:10.1016/j.micres.2016.06.008
Pan, X., Wang, H., Tong, D., Wang, C., Sun, L., Zhao, C., . . . Wu, D. (2016). Physcion induces apoptosis in hepatocellular carcinoma by modulating miR-370. Am J Cancer Res,6(Dec), 12th ser., 2919-2931. PMID: 28042511
Si, X., Zhang, X., Hao, X., Li, Y., Chen, Z., Ding, Y., . . . Zhou, Y. (2016). Upregulation of miR-99a is associated with poor prognosis of acute myeloid leukemia and promotes myeloid leukemia cell expansion. Oncotarget,7(47). doi:10.18632/oncotarget.12947
Tang, Y., Cui, Y., Li, Z., Jiao, Z., Zhang, Y., He, Y., . . . Zhang, S. (2016). Radiation-induced miR-208a increases the proliferation and radioresistance by targeting p21 in human lung cancer cells. Journal of Experimental & Clinical Cancer Research,35(1). doi:10.1186/s13046-016-0285-3
Yang, H., Zhu, Q., Zhou, N., & Tian, Y. (2016). Optimized expression of prolyl aminopeptidase in Pichia pastoris and its characteristics after glycosylation. World Journal of Microbiology and Biotechnology,32(11). doi:10.1007/s11274-016-2135-z
Zhi, N., Wan, Z., Liu, X., Wong, S., Kim, D. J., Young, N. S., & Kajigaya, S. (2010). Codon Optimization of Human Parvovirus B19 Capsid Genes Greatly Increases Their Expression in Nonpermissive Cells. Journal of Virology,84(24), 13059-13062. doi:10.1128/jvi.00912-10
Gene Cloning
Campanella J J, Kurdach S, Skibitski R, et al. Evidence for the Early Evolutionary Loss of the M20D Auxin Amidohydrolase Family from Mosses and Horizontal Gene Transfer from Soil Bacteria of Cryptic Hydrolase Orthologues to Physcomitrella patens[J]. Journal of Plant Growth Regulation, 2019: 1-11. doi:10.1007/s00344-019-09945-6
Hu, J., Tian, J., Li, F., Xue, B., Hu, J., Cheng, X., . . . Li, B. (2017). Clone and functional analysis of Seryl-tRNA synthetase and Tyrosyl-tRNA synthetase from silkworm, Bombyx mori. Scientific Reports,7(1). doi:10.1038/srep41563
Yan, H., Zhang, Y., Zhang, Y., Ren, X., Shen, Y., Cheng, M., & Zhang, Y. (2017). CRIF1 enhances p53 activity via the chromatin remodeler SNF5 in the HCT116 colon cancer cell lines. Biochimica Et Biophysica Acta (BBA) – Gene Regulatory Mechanisms,1860(4), 516-522. doi:10.1016/j.bbagrm.2017.02.006
CRISPR-Cas9 sgRNA
Li J, Chen Z, Chen F, et al. Targeted mRNA demethylation using an engineered dCas13b-ALKBH5 fusion protein[J]. bioRxiv, 2019: 614859. doi:10.1101/614859
Zheng S, Liu Q, Ma R, et al. Let‐7b‐5p inhibits proliferation and motility in squamous cell carcinoma cells through negative modulation of KIAA1377[J]. Cell biology international, 2019. doi:10.1002/cbin.11136
Lu, Y., Ye, X., Guo, R., Huang, J., Wang, W., Tang, J., . . . Qian, Y. (2017). Genome-wide Targeted Mutagenesis in Rice Using the CRISPR/Cas9 System. Molecular Plant,10(9), 1242-1245. doi:10.1016/j.molp.2017.06.007
Codon Optimization
Zhang P, Wang Z P, Sheng J, et al. High and efficient isomaltulose production using an engineered Yarrowia lipolytica strain[J]. Bioresource technology, 2018, 265: 577-580. doi:10.1016/j.biortech.2018.06.081
Liu, B., Kong, Q., Zhang, D., & Yan, L. (2018). Codon optimization significantly enhanced the expression of human 37-kDa iLRP in Escherichia coli. 3 Biotech,8(4). doi:10.1007/s13205-018-1234-y
Jin, W., Li, S., Chen, J., Liu, B., Li, J., Li, X., . . . Zhong, W. (2018). Increased soluble heterologous expression of a rat brain 3- O -sulfotransferase 1 – A key enzyme for heparin biosynthesis. Protein Expression and Purification,151, 23-29. doi:10.1016/j.pep.2018.06.007
Zhang, P., Wang, Z., Sheng, J., Zheng, Y., Ji, X., Zhou, H., . . . Chi, Z. (2018). High and efficient isomaltulose production using an engineered Yarrowia lipolytica strain. Bioresource Technology,265, 577-580. doi:10.1016/j.biortech.2018.06.081
Oligo Synthesis
Zhou S, Tao M, Wang Y, et al. Effects of CYP3A4* 1G and CYP3A5* 3 polymorphisms on pharmacokinetics of tylerdipine hydrochloride in healthy Chinese subjects[J]. Xenobiotica, 2019, 49(3): 375-380. doi:10.1002/bies.950050611
He Q, Zhu S, Lin M, et al. Increased GPR120 level is associated with gestational diabetes mellitus[J]. Biochemical and biophysical research communications, 2019. doi:10.7150/ijbs.31009
Nan M, Bi Y, Xue H, et al. Rapid Determination of Ochratoxin A in Grape and Its Commodities Based on a Label-Free Impedimetric Aptasensor Constructed by Layer-by-Layer Self-Assembly[J]. Toxins, 2019, 11(2): 71. doi:10.3390/toxins11020071
Wang Z, Fang J, Xiao J. Correlation of the expression of inflammatory factors with expression of apoptosis-related genes Bax and Bcl-2, in burned rats[J]. Experimental and therapeutic medicine, 2019, 17(3): 1790-1796. doi:10.3892/etm.2018.7118
Liu X, Zhang Y, Liu H, et al. RNA interference in the oleaginous yeast Rhodosporidium toruloides[J]. FEMS yeast research, 2019. doi:10.1093/femsyr/foz031
Huang X, Xue J, Wang F Z, et al. Enhanced protoplast assay by transfecting PCR-assembled gene expression cassettes with telomeric repeats and thiophosphate modifications[J]. Analytical biochemistry, 2019, 569: 39-45. doi:10.1016/j.ab.2019.01.003
Wang J, Huang J, Zhu M, et al. Osteopontin potentiates PM-induced IL-1α and IL-1β production via the ERK/JNK signaling pathway[J]. Ecotoxicology and environmental safety, 2019, 171: 467-474. doi:10.1016/j.ecoenv.2019.01.005
He Q, Zhu S, Lin M, et al. Increased GPR120 level is associated with gestational diabetes mellitus[J]. Biochemical and biophysical research communications, 2019. doi:10.1016/j.bbrc.2019.03.034
Chen M, Wu Y, Yu S, et al. Drug Resistance and Integron Genes in Escherichia coli Isolated from Urinary Tract Infection[J]. Journal of nanoscience and nanotechnology, 2019, 19(9): 5989-5993. doi:10.1166/jnn.2019.16501
Wang, J., Zhu, M., Wang, L., Chen, C., & Song, Y. (2019). Amphiregulin potentiates airway inflammation and mucus hypersecretion induced by urban particulate matter via the EGFR-PI3Kα-AKT/ERK pathway. Cellular Signalling,53, 122-131. doi:10.1016/j.cellsig.2018.10.002
Li X, Huang X, Zhang J, et al. A novel peptide targets CD105 for tumour imaging in vivo[J]. Oncology reports, 2018, 40(5): 2935-2943. doi:10.3892/or.2018.6643
Shen P, Chen J, Pan M. The protective effects of total paeony glycoside on ischemia/reperfusion injury in H9C2 cells via inhibition of the PI3K/Akt signaling pathway[J]. Molecular medicine reports, 2018, 18(3): 3332-3340. doi:10.3892/mmr.2018.9335
Cheng Y, Chen G, Wang L, et al. Triptolide-induced mitochondrial damage dysregulates fatty acid metabolism in mouse sertoli cells[J]. Toxicology letters, 2018, 292: 136-150. doi:10.1016/j.toxlet.2018.04.035
Chen, S., Yang, J., Zhang, Y., Duan, C., Liu, Q., Huang, Z., . . . Xu, G. (2018). Ubiquitin-conjugating enzyme UBE2O regulates cellular clock function by promoting the degradation of the transcription factor BMAL1. Journal of Biological Chemistry,293(29), 11296-11309. doi:10.1074/jbc.ra117.001432
Fang, B., Chen, X., Wu, M., Kong, H., Chu, G., Zhou, Z., . . . Chen, B. (2018). Luteolin inhibits angiogenesis of the M2‑like TAMs via the downregulation of hypoxia inducible factor‑1α and the STAT3 signalling pathway under hypoxia. Molecular Medicine Reports. doi:10.3892/mmr.2018.9250
Nie, H., Nie, D., & Men, L. (2018). Role of miR-214 in modulating proliferation and invasion of human colon cancer SW620 cells. Oncology Letters. doi:10.3892/ol.2018.9521
Sun, Y., Zou, H., Yang, L., Zhou, M., Shi, X., Yang, Y., . . . Lu, Y. (2018). Effect on the liver cancer cell invasion ability by studying the associations between autophagy and TRAP1 expression. Oncology Letters. doi:10.3892/ol.2018.8774
Zhang, H., Zhang, Z., Jia, L., Ji, W., & Li, H. (2018). Genetic Polymorphism in the RYR1 C6487T Is Associated with Severity of Hypospadias in Chinese Han Children. BioMed Research International,2018, 1-7. doi:10.1155/2018/7397839
Wang, J., Wang, F., Zhu, J., Song, M., An, J., & Li, W. (2018). Transcriptome Profiling Reveals PHLDA1 as a Novel Molecular Marker for Ischemic Cardiomyopathy. Journal of Molecular Neuroscience,65(1), 102-109. doi:10.1007/s12031-018-1066-6
Zhang, Y., Pan, C., Wang, J., Cao, J., Liu, Y., Wang, Y., & Zhang, L. (2017). Genetic and immune features of resectable malignant brainstem gliomas. Oncotarget,8(47). doi:10.18632/oncotarget.19653
Zhang, Z., Liu, Y., Liu, P., Yang, L., Jiang, X., Luo, D., & Yang, D. (2017). Non-invasive detection of gastric cancer relevant d-amino acids with luminescent DNA/silver nanoclusters. Nanoscale,9(48), 19367-19373. doi:10.1039/c7nr07337b
Yu, D., Ye, T., Xiang, Y., Shi, Z., Zhang, J., Lou, B., . . . Zhou, M. (2017). Quercetin inhibits epithelial–mesenchymal transition, decreases invasiveness and metastasis, and reverses IL-6 induced epithelial–mesenchymal transition, expression of MMP by inhibiting STAT3 signaling in pancreatic cancer cells. OncoTargets and Therapy,Volume 10, 4719-4729. doi:10.2147/ott.s136840
Wang, J., Huang, J., Wang, L., Chen, C., Yang, D., Jin, M., . . . Song, Y. (2017). Urban particulate matter triggers lung inflammation via the ROS-MAPK-NF-κB signaling pathway. Journal of Thoracic Disease,9(11), 4398-4412. doi:10.21037/jtd.2017.09.135
Wang, Q., Wang, Y., Xing, Y., Yan, Y., Guo, P., Zhuang, J., . . . Zhang, J. (2016). Physcion 8- O -β-glucopyranoside induces apoptosis, suppresses invasion and inhibits epithelial to mesenchymal transition of hepatocellular carcinoma HepG2 cells. Biomedicine & Pharmacotherapy,83, 372-380. doi:10.1016/j.biopha.2016.06.045
Probe Synthesis
Mei J, Yan T, Huang Y, et al. A DAAM1 3′-UTR SNP mutation regulates breast cancer metastasis through affecting miR-208a-5p-DAAM1-RhoA axis[J]. Cancer Cell International, 2019, 19(1): 55. doi:10.1186/s12935-019-0747-8
Eastwood, M. P., Deprest, J., Russo, F. M., Wang, H., Mulhall, D., Iwasiow, B., . . . Keijzer, R. (2018). MicroRNA 200b is upregulated in the lungs of fetal rabbits with surgically induced diaphragmatic hernia. Prenatal Diagnosis,38(9), 645-653. doi:10.1002/pd.5318
Wu, Y., Li, X., Tan, X., Feng, D., Yan, J., Zhang, H., . . . Han, H. (2018). A cyclic catalysis enhanced electrochemiluminescence aptasensor based 3D graphene/photocatalysts Cu 2 O-MWCNTs. Electrochimica Acta,282, 672-679. doi:10.1016/j.electacta.2018.06.104
Zhang, Y., Pan, C., Wang, J., Cao, J., Liu, Y., Wang, Y., & Zhang, L. (2017). Genetic and immune features of resectable malignant brainstem gliomas. Oncotarget,8(47). doi:10.18632/oncotarget.19653
Sequencing
Fei Z, Li S, Wang J, et al. Rhodotorula glutinis as a living cell liposome to deliver polypeptide drugs in vivo[J]. Drug delivery, 2019, 26(1): 51-62. doi:10.1080/10717544.2018.1551439
Chen, M., Zhai, J., Liu, Y., Xue, B., Hu, J., Cheng, X., . . . Li, B. (2018). Molecular cloning and characterization of C 1 tetrahydrofolate (C 1 -THF) synthase in Bombyx mori , silkworm. Gene,663, 25-33. doi:10.1016/j.gene.2018.04.037
Yang, F., Guo, L., Lyu, K., Zhang, J., Yang, Y., Wang, H., . . . Huo, Y. (2018). Local Polyploidy Phenomenon inEscherichia coliand its significance in genetic engineering. doi:10.1101/335448
Cheng, H., Luo, Z., Lu, M., Gao, S., & Wang, S. (2017). The hyperthermophilic α-amylase from Thermococcus sp. HJ21 does not require exogenous calcium for thermostability because of high-binding affinity to calcium. Journal of Microbiology,55(5), 379-387. doi:10.1007/s12275-017-6416-5
Tang, X., Li, P., Zhang, Q., Zhang, Z., Zhang, W., & Jiang, J. (2017). Time-Resolved Fluorescence Immunochromatographic Assay Developed Using Two Idiotypic Nanobodies for Rapid, Quantitative, and Simultaneous Detection of Aflatoxin and Zearalenone in Maize and Its Products. Analytical Chemistry,89(21), 11520-11528. doi:10.1021/acs.analchem.7b02794
Vector Construction
Wu Y, Deng Y, Zhu J, et al. Pim1 promotes cell proliferation and regulates glycolysis via interaction with MYc in ovarian cancer[J]. OncoTargets and therapy, 2018, 11: 6647. doi:10.2147/OTT.S180520
Bellido, F., Sowada, N., Mur, P., Lázaro, C., Pons, T., Valdés-Mas, R., . . . Valle, L. (2018). Association Between Germline Mutations in BRF1 , a Subunit of the RNA Polymerase III Transcription Complex, and Hereditary Colorectal Cancer. Gastroenterology,154(1). doi:10.1053/j.gastro.2017.09.005
Chu, J., Li, Y., Fan, X., Ma, J., Li, J., Lu, G., . . . Yuan, H. (2018). MiR-4319 Suppress the Malignancy of Triple-Negative Breast Cancer by Regulating Self-Renewal and Tumorigenesis of Stem Cells. Cellular Physiology and Biochemistry,48(2), 593-604. doi:10.1159/000491888
Xu, X., Song, C., Chen, Z., Yu, C., Wang, Y., Tang, Y., & Luo, J. (2018). Downregulation of HuR Inhibits the Progression of Esophageal Cancer through Interleukin-18. Cancer Research and Treatment,50(1), 71-87. doi:10.4143/crt.2017.013
DNA Storage
Zhong, Y., Qi, S., Sheng, F., Tian, J., Zhu, P., Yang, P., & Cai, X. (2017). A new digital information storing and reading system based on synthetic DNA. Science China Life Sciences,61(6), 733-735. doi:10.1007/s11427-017-9131-7
RNA Interference
Ren, Y., Chen, J., Wu, X., Gui, C., Mao, K., Zou, F., & Li, W. (2018). Role of c-Abl-GSK3β Signaling in MPP -Induced Autophagy-Lysosomal Dysfunction. Toxicological Sciences,165(1), 232-243. doi:10.1093/toxsci/kfy155
RNA Synthesis
Zhang C, Zhang Z, Chang Z, et al. miR‐193b‐5p regulates chondrocytes metabolism by directly targeting histone deacetylase 7 in interleukin‐1β‐induced osteoarthritis[J]. Journal of cellular biochemistry, 2019. doi:10.1002/jcb.28545
Peng J, Zhou F, Wang Y, et al. Differential response to lead toxicity in rat primary microglia and astrocytes[J]. Toxicology and applied pharmacology, 2019, 363: 64-71. doi:10.1016/j.taap.2018.11.010
Feng Q, Yang W, Gao Z, et al. Up-regulation of P-gp via NF-κB activation confers protection against oxidative damage in the retinal pigment epithelium cells[J]. Experimental eye research, 2019, 181: 367-373. doi:10.1016/j.exer.2018.11.024
Du K T, Deng J Q, He X G, et al. MiR-214 regulates the human hair follicle stem cell proliferation and differentiation by targeting EZH2 and Wnt/β-catenin signaling way in vitro[J]. Tissue engineering and regenerative medicine, 2018, 15(3): 341-350. doi:10.1007/s13770-018-0118-x
Chang Z, Meng F, Zhang Z, et al. MicroRNA‐193b‐3p regulates matrix metalloproteinase 19 expression in interleukin‐1β‐induced human chondrocytes[J]. Journal of cellular biochemistry, 2018, 119(6): 4775-4782. doi:10.1002/jcb.26669
Plasmid Preparation
Dong H, Cao W, Xue J. Long noncoding FOXD2-AS1 is activated by CREB1 and promotes cell proliferation and metastasis in glioma by sponging miR-185 through targeting AKT1[J]. Biochemical and biophysical research communications, 2019, 508(4): 1074-1081.2018. doi:10.1016/j.bbrc.2018.12.050
Sayas C L, Medina M, Cuadros R, et al. Role of tau N-terminal motif in the secretion of human tau by end binding proteins[J]. PloS one, 2019, 14(1): e0210864. doi:10.1371/journal.pone.0210864
Ho N T T, Kutzner A, Heese K. A Novel Divergent Gene Transcription Paradigm—the Decisive, Brain-Specific, Neural|-Srgap2–Fam72a-| Master Gene Paradigm[J]. Molecular neurobiology, 2019: 1-9. doi:10.1007/s12035-019-1486-5
Bellido F, Sowada N, Mur P, et al. Association between germline mutations in BRF1, a subunit of the RNA polymerase III transcription complex, and hereditary colorectal cancer[J]. Gastroenterology, 2018, 154(1): 181-194. e20. doi:10.3791/1135
Site-Directed Mutagenesis
Chen M, Zheng F, Yuan G, et al. Development of an infectious cell culture system for hepatitis C virus genotype 6a clinical isolate using a novel strategy and its sensitivity to direct-acting antivirals[J]. Frontiers in microbiology, 2018, 9. doi:10.3389/fmicb.2018.02950
Antibody Discovery Services
Xu Z, Zhou X, Chen G. Expression and Mechanism of Interleukin 1 (IL-1), Interleukin 2 (IL-2), Interleukin 8 (IL-8), BMP, Fibroblast Growth Factor 1 (FGF1), and Insulin-Like Growth Factor (IGF-1) in Lumbar Disc Herniation[J]. Medical science monitor: international medical journal of experimental and clinical research, 2019, 25: 984. doi: 10.12659/MSM.911910
High Throughput Gene Synthesis
Rai K M, Ghose K, Rai A, et al. Genome Engineering Tools in Plant Synthetic Biology[M]//Current Developments in Biotechnology and Bioengineering. Elsevier, 2019: 47-73. doi:10.1016/B978-0-444-64085-7.00003-4
Peptide Sequence Synthesis
Jiao X, Sun W, Zhang Y, et al. Exchanging the order of carotenogenic genes linked by porcine teschovirus-1 2A peptide enable to optimize carotenoid metabolic pathway in Saccharomyces cerevisiae[J]. RSC Advances, 2018, 8(61): 34967-34972. doi:10.1039/C8RA06510A