Human protein kinase sgRNA Panel

With our proprietary CRISPR-Cas9 sgRNA design platform, Synbio Technologies has designed 10 sgRNAs for each target gene, and constructed the CRISPR-Cas9 sgRNA Panel libraries. The delivery of these libraries includes plasmid, lentivirus, ready-to-use sgRNA, and more.We provide integrated sgRNA for every gene in panels promoting cancer development and evolution, cell cycle pathway target screening, and cell pathway genetics screening research.

AGC Protein Kinase Family

MRCKα
LATS1PKCηMSK2 PKG2PKG1
MRCKβAKT1PKCεP70s6kGPRK4PDK1
DMPK2AKT2PKCδP70s6kbGPRK6YANK2
DMPK1AKT3PKCθRSK2RHODK/GRK1YANK1
ROCK1SGK1PKCIRSK1/P90RSKGPRK7YANK3
ROCK2SGK3PKCZRSK3PRKYSGK494
CRIKSGK2PKN1/PRK1RSK4PRKXRSKL1
NDR1PKCαPKN2/PRK2BARK2/GRK3PKACαRSKL2
NDR2PKCβPKN3BARK1/GRK2PKACβMAST1
LATS2PKCγMSK1GPRK5PKACγMAST4
MAST2MAST3MASTL

CAMK Protein Kinase Family

CaMK1βDRAK1CaMK2βMNK2QSKTSSK4
CaMK1αskMLCK/MYLKCaMK2γAMPKα1NuaK1/ARK5PIM1
CaMK1δcaMLCKCASKAMPKα2NuaK2PIM3
CaMK1γSDgK085PHKγ2BRSK2NIM1PIM2
CaMK4smMLCK/MYLKPHKγ1BRSKSNRKSgK4155
VACAMKLTiTIN/TTNDCAMKL1MELKPASKTrb1
PSKH1SPEG/APEG1DCAMKL2MARK1CHK1Trb2
PSKH2ObscurinDCAMKL3MARK2LKB1Trb3
DAPK1TradMAPKAPK2MARK3HUNKSTK33
DAPK3TrioMAPKAPK3MARK4TSSK1PKD1/PKCμ
DAPK2CaMK2αMAPKAPK5QIK/SIK2SSTKPKD3
DRAK2CaMK2δMNK1SIKTSSK3PKD2
CHK2

CK1 Protein Kinase Family

CK1αCK1α2CK1δCK1εCK1γ1CK1γ3
CK1γ2TTBK1TTBK2VRK1VRK2VRK3

CMGC Protein Kinase Family

CDK2CDK4ERK2P38γGSK3βHIPK3
CDK3CDK8ERK1ERK7CLK1HIPK2
CDC2/CDK1CDK11ERK5ERK4CLK4HIPK1
CDK5CDK10NLKERK3CLK3HIPK4
PCTAIRE1PITSLREJNK3CDKL5CLK2PRP4
PCTAIRE2CDK9JNK1CDKL1DYRK1ASRPK2
PCTAIRE3CHEDJNK2CDKL4DYRK1BMSSK1
PFTAIRE1CRK7P38αCDKL3DYRK4SRPK1
PFTAIRE2CDK7P38βCDKL2DYRK2MOK
CDK6CCRKP38δGSK3αDYRK3ICK
MAK

STE Protein Kinase Family

MEKK3/MAP3K3MEK1/MAP2K1NIKPAK4TAO2/PSKMYO3B
MEKK2/MAP3K2MEK2/MAP2K2STLK3/SPAKPAK5TAO1KHS1
MAP3K8MEK5/MAP2K5OSR1PAK6TAO3/JIKKHS2
MEKK1/MAP3K1MKK3/MAP2K3STLK6/ALS2CR2MST1ZC1/HGKGCK
MAP3K4MKK6/MAP2K6STLK5/LYK5MST2ZC3/MINKHPK1
TAK1/MAP3K7MKK4/SEK1/MAP2K4PAK2MST3ZC2/TNIKLOK
ASK1/MAP3K5MKK7/MAP2K7PAK1MST4ZC4/NRKSLK
ASK2/MAP3K6COT/TPL2PAK3YSK1/SOK1MYO3A

TK Protein Kinase Family

ABLBLKHER4/ErbB4EphA6METPDGFRβ
ARGFRKHER3/ErbB3EphA7RONFLT3
BTKBRKFAKEphA8RYKTIE2/TEK
BMX/ETKPYK2EphA2FGFR1TIE1 SRM
ITKCTK/MATKZAP70EphA10FGFR3CCK4
TXKCSKSYKEphB6FGFR2DDR2
TECACKEphA1ALKFGFR4DDR1
FGRTNK1EphB4LTKROSRETTRKA
SRCJAK2EphB2IGF1RFLT4/VEGFR3TRKC
YESJAK3EphB1INSRFLT1/VEGFR1TRKB
FYNJAK1EphB3IRRKDR/VEGFR2MUSK
LCKTYK2EphA4MERKITROR2
LYNEGFREphA3AXLCSF1R/FMSROR1
HCKHER2/ErbB2EphA5TYRO3/SKYPDGFRαLMR1/AATK
LMR2LMR3SuRTK106FESFER

TKL Protein Kinase Family

IRAK4LIMK2ALK2B-RAFTAK1MLK4
IRAK1TESK1BMPR1ARAF1LIKMLK2
IRAK3TESK2BMPR1BA-RAFDLKZAK
IRAK2LRRK1TGFβR1KSR1LZKRIPK2
MLKLLRRK2MISR2KSR2MLK1ANKRD3
LIMK1ALK1BMPR2HH498MLK3SgK288
RIPK3RIPK1

Atypical Protein Kinase Family

ADCK1Chak2Brd3PDHK4SMG1TIF1γ
ADCK5Alphak3Brd4BCKDKTRRAPTIF1β
ADCK3EEF2KBrdTATMRIOK3
ADCK4Alphak2PDHK2ATRRIOK1
ADCK2Alphak1PDHK3MTOR/FRAPRIOK2
Chak1Brd2PDHK1DNAPKTIF1α

Other Protein Kinase Family

AURAULK2NEK5Wee1SgK1155NRBP2
AURBULK3NEK6Wee1BKISWnk1
AURCIKKβNEK7MYT1SgK493/RIOK2Wnk3
PLK1IKKα/CHUKNEK8CDC7IRE2/ERN2Wnk2
PLK2IKKεNEK9CK2α1IRE1/ERN1Wnk4
PLK3TBK1NEK10CK2α2CLIK1LSlob
PLK4GAKNEK11SBKCLIK1SCYL1
TLK1AAK1TTKSgK069SgK071SCYL3/CCL15
TLK2BIKE/BMP2KMOSSgK110PINK1SCYL2/CCL14
CaMKK1MPSK1TOPK/PBKSgK4155SgK223PIK3R4
CaMKK2NEK1GCN2BUB1SgK269RNAsel
FusedNEK2PEK/PERKBUBR1SgK307/TEX14STK31
ULK4NEK3PKRPRPKSgK424TBCK
ULK1NEK4HRIHaspinNRBP1