Oligo Synthesis

Synbio Technologies’ oligo synthesis platform equips state-of-the-art synthesizers and leading professional teams experienced in the oligo synthesis as well as modification technologies. This allows us to provide high-quality oligo products to scientific researchers and industrial customers around the world. By leveraging our advanced and innovative manufacturing process, Synbio Technologies offers a wide range of oligo & probe synthesis options, including custom DNA oligos, diagnostic oligos & probes, NGS oligos, modified oligos, antisense oligos, CpG ODNs, etc. In addition, we also provide high-throughput oligo library and oligo pool synthesis to customers with large-scale oligo projects. Synbio Technologies is always competent to offer tailor-made approached to accomplish every request to oligo synthesis.

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Recommended for orders containing more than 96 sequences

Why us?


Certified with the highest manufacturing standards (ISO9001 & ISO13485), stringent QC & QA standards, large-scale sequencing verifying the average mutation rate to be lower than 1/1000.


Various highly customizable options of purification, specifications and delivery forms, and flexible synthesis scale is available upon request all well.


Qualified and available for multiple applications such as molecular diagnosis, chip sequencing, genome engineering, tumor research, forensic identification, precision medicine, IVD, digital information storage, etc.

Standard Oligo Synthesis Process

Based on customers’ various requests, Synbio Technologies’ scientific teams will performance proprietary DNA sequence analysis and design. CpG-based chemical oligo synthesis will be finished by utilizing industry leading manufacture process. For final sequence verification, MS analysis and other stringent quality control method will be conducted step by step.


Oligo Synthesis Services

Service OptionsSpecificationsDelivarables
Custom DNA OligosProviding standard unmodified DNA oligo synthesis. It includes standard oligos, micro-scale oligos, large-scale oligos, degenerate primers, as well as long oligos.Standard package:
  1. Lyophilized Dry powder: 2 OD oligo, 1 tube (transparent or dark)
  2. Certificate of Analysis (COA): includes sequence information, OD, Tm, etc.
Diagnostic Oligos & ProbesProviding the services of FISH probes, qPCR probes, SNP probes, and other molecular diagnostic materials.
NGS OligosHigh quality oligos with enhanced purity and accuracy for Next Generation Sequencing (NGS).
Modified OligosComprehensive oligo modification and labeling services, such as special bases, dU/dI, phosphorothioate, phosphorylation, spacers, amino, biotin, FAM, HEX, ROX, BHQ, etc.
Antisense OligosStrictly comply with QC testing standards and HPLC purity detection is used to ensure the high quality output of all our ASO products.
CpG ODNsProviding three types of CpG ODNs (Class A, Class B, and Class C) of various species.
Oligo LibrariesUsing high-throughput semiconductor chip synthesis technology to provide customers with the design and synthesis of various library oligos, including oligo pools, trimer oligos, and sgRNA library oligos.
Oligo PoolsHigh throughput oligo synthesis, up to 1 million oligos can be synthesized on a single chip within one synthetic circle.