Target region enrichment technology enables specific hybridization between probes and genomic regions of interest in various high throughput sequencing techniques. Well-designed probes can effectively capture SNPs, known or unknown mutation (indels, inversion, recombination, etc) and many clinical tumor-related genomic regions.
Based on our qualified and optimized oligo design and synthesis platform, Synbio Technologies can offer custom hybrid capture probes and a series of sequence capture probes for personalized drug or disease susceptibility gene variation research. Using this platform, we can design and synthesize labeled capture probes in solution or on-chip to achieve high specificity and deep reads. The generated probes are typically utilized in the whole exome sequencing (WES), target region sequencing (TRS), etc.
- Multiple probe schemes including individually synthesized single probe or high-throughput probe pool.
- High sequence accuracy and specificity, effectively improving capture efficiency.
- Target region enrichment, reducing sequencing cost and the difficulty of massive data analysis.
- Customizable services with reliable quality and high performance.