RNA Modifications

Synbio Technologies provides extensive modifications options for synthesized RNA, making it convenient for customers to choose flexible and diverse modifications and fluorescent labeling according to the function of synthesized RNA sequences. The modification of an RNA sequence can help the RNA to be delivered to the cell while increasing the stability of RNA sequence, avoiding degradation by nuclease, such as phosphorothioate, 2’-OMe, and 2’-F modifications. The advantage of fluorescent labeling in RNA is to let the synthesized RNA be observed or located by fluorescence microscopy and confocal laser microscopy, while also using it as a nucleic acid detection tool to perform virus detection, disease diagnosis, and early tumor screening.

Competitive Advantages

  • Experienced Staff: Professional staff and exceptional expertise in RNA synthesis offer the most optimal, customized solutions using standardized experimental procedures.
  • Comprehensive Modifications and Fluorescent Labeling: Modification or fluorescent labeling of your RNA sequence is tailored to meet your customized requirements.
  • Cost-Effective: Competitive prices and affordable services.

RNA Modifications and Fluorescence Labeling

RNA ModificationsRNA Fluorescence
Groups/Quenchers Labeling
Dual/Multiple Labeling
Modified Bases
  • 2′-O-Methyl
  • 2′ Fluoro
  • m6A
  • 5’ Cy3
  • 3′ Cy3
  • 5’ Cy5
  • 3′ Cy5
  • 5’ FAM
  • 3′ FAM
  • 5′ ROX
  • 3′ ROX
  • 5’HEX
  • 5’TAMRA
  • 5’TET
  • 3’BHQ-1
  • 3’DABCYL
  • 3’TAMRA
  • 5′ FAM-3′ BHQ1
  • 5′ HEX-3′ BHQ1
  • 5′ TET-3′ BHQ-1
  • 5′ FAM-3′ MGB
  • 5′ FAM-3′ TAMRA
  • 5′ HEX-3′ TAMRA
  • 5′ TET-3′ TAMRA
  • 5′ HEX-3′ MGB
  • 5′ TET-3′ MGB
  • 5′ FAM-3′ DABCYL
  • 5′ HEX-3′ DABCYL
  • 5′ Phos-3′ FAM
  • 5’TAMRA-3’Phos
  • 5’C6-Biotin-3’Cy5
Phosphorothioates
  • P-S
Phosphorylation
  • 5’- PHO
  • 3′- PHO
Amino Linkers
  • 5’-NH2 C6
  • 3’-NH2 C7
Thiol
  • 5’-SH C6
  • 3’-SH C3
Biotin
  • 5′ Biotin
Digoxigenin
  • 5′ DIG
  • 3′ DIG
Please contact us to query about the other kinds of modified RNA (quote@synbio-tech.com).