Synbio Technologies provides comprehensive modifications and labeling services to meet our customers’ specified research requirements. Our industry leading professional team utilizes state-of-the-art synthesizers to achieve both oligo synthesis and modifications. Our stringent quality control guidelines ensure the synthesis of high-quality modified oligos and subsequently delivered in a timely manner. We can satisfy various research needs in biology, diagnostics, personal medicine, drug discovery, etc.
Synbio Technologies’ custom DNA oligos are designed and synthesized with rigorous quality control to ensure that overall quality while meeting our customers’ every request. Our specialized services include oligonucleotides modified with special bases, dU/dI, phosphorothioates, phosphorylation, spacers, amino linkers, disulfide linkers, biotin, digoxin, etc. Synbio Technologies also provides multiple fluorescent groups and quenchers at 3’, 5’ or designated sites specified by the customer. This includes FAM, HEX, ROX, BHQ and Texas Red, etc. The resulting oligos can be used in a variety of applications, including PCR, cloning, sequence verification, and gene detection.
Competitive Advantages
Comprehensive Modifications and Labeling:
- Stringent ISO9001: 2015 Certified Processing for oligo synthesis, meticulously monitored and advanced traceability
Multiple Purification Options:
Technical Support:
Large-scale sequencing verifying the average mutation rate to be lower than 1/1000
Include desalt, PAGEE Plus, PAGEE, RP-HPLC, IE-HPLC and Dual HPLC
Professional teams experienced in oligo synthesis and various modifications offer support throughout the production progress
Service Specifications
| Classifications | Modifications | Purification | |
|---|---|---|---|
| (10-45bp) | (46-80bp) | ||
| Modified Bases | dU | RP-HPLC | PAGE&RP-HPLC |
| dI | |||
| 5-Methyl dC | |||
| DBCO | 5’ DBCO | RP-HPLC | RP-HPLC |
| 3’ DBCO | PAGE&RP-HPLC | ||
| dT-DBCO | |||
| AMCA | 5’ AMCA | RP-HPLC | RP-HPLC |
| 3’ AMCA | PAGE&RP-HPLC | ||
| dT-AMCA | |||
| Phosphorothioates | SPO3 | RP-HPLC | PAGE&RP-HPLC |
| Amino Linkers | 5’Amino C6 | RP-HPLC | PAGE&RP-HPLC |
| dT-Amino C6 | |||
| 3’Amino C7 | |||
| 5’Amino C12 | RP-HPLC | ||
| Biotin | 5’Biotin | RP-HPLC | RP-HPLC |
| 3’Biotin | PAGE&RP-HPLC | ||
| dT-Biotin | |||
| Digoxigenin | 5’Digoxigenin | RP-HPLC | RP-HPLC |
| 3’Digoxigenin | PAGE&RP-HPLC | ||
| dT-Digoxigenin | |||
| Phosphorylation | 5’ PO4 | RP-HPLC | PAGE&RP-HPLC |
| 3’ PO4 | |||
| Hydrosulphonyl | 5’ HS-C6 | RP-HPLC | RP-HPLC |
| 3’ HS-C3 | PAGE&RP-HPLC | ||
| Locked Nuleic Acid | LNA (A/G/C/U) | RP-HPLC | PAGE&RP-HPLC |
| Fluoro Bases | 2’-F-2’-dA 2’-F-2’-dC 2’-F-2’-dG 2’-F-2’-dU | RP-HPLC | PAGE&RP-HPLC |
| Spacer | dSpacer | RP-HPLC | PAGE&RP-HPLC |
| Spacer C3 | |||
| Spacer C9 | |||
| Spacer C18 | |||
Standard Deliverables
- Lyophilized dry DNA oligo powder
- 1 tube (Transparent or dark) or 96-well and 384-well plate
- Certificate of Analysis (COA) including sequencing information, OD, Tm, etc.
How to Order Oligo Modification & Labeling
If you have any questions, please feel free to contact us anytime for assistance during business hours. Our experienced project managers will provide you with professional support to ensure the success of your project.
 Online Inquiry |  quote@synbio-tech.com |  +1 732-230-3003 |  +1 609 228 5911 |
